1,4-PBIT (dihydrobromide)
1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively[1].
Product Specifications
CAS Number
[157254-60-9]
Product Name Alternative
1,4-PB-ITU (dihydrobromide)
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-4-pbit-dihydrobromide.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
NC(SCCC1=CC=C(CCSC(N)=N)C=C1)=N.[H]Br.[H]Br
Molecular Formula
C12H20Br2N4S2
Molecular Weight
444.25
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ENOS; iNOS; nNOS
Available Sizes
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