8-Bromooctanoic acid
8-Bromooctanoic acid is a PROTAC linker, and can be used for synthesis of PROTAC CYP1B1 degrader-2 (HY-158429) [1].
Product Specifications
CAS Number
[17696-11-6]
UNSPSC
12352211
Hazard Statement
H314
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-bromooctanoic-acid.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCCCCBr
Molecular Formula
C8H15BrO2
Molecular Weight
223.11
Precautions
H314
References & Citations
[1]Yao X, et al. Development of novel N-aryl-2,4-bithiazole-2-amine-based CYP1B1 degraders for reversing drug resistance. Eur J Med Chem. 2024 Jun 5;272:116488.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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