(22S,23S) -Homobrassinolide

(22S,23S) -Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S) -Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active[1].

Product Specifications

CAS Number

[80483-89-2]

Product Name Alternative

SSHB

UNSPSC

12352005

Target

Akt; Endogenous Metabolite; PI3K

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; PI3K/Akt/mTOR

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/22s-23s-homobrassinolide.html

Concentration

10mM

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)[C@H](O)[C@@H](O)[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@]([C@@]4([C@@](C[C@H](O)[C@H](O)C4)([H])C(OC3)=O)C)([H])CC1

Molecular Formula

C29H50O6

Molecular Weight

494.70

References & Citations

[1]Esposito D, et al. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J Med Chem. 2011;54 (12) :4057-4066. |[2]Dahse I, et al. Effects of (22S,23S) -Homobrassinolide and Related Compounds on Membrane Potential and Transport of Egeria Leaf Cells. Plant Physiol. 1990;93 (3) :1268-1271.