NCI172112
NCI172112 is a classical bifunctional alkylating agent synthesized in an effort to develop antitumor agents effective against CNS tumors.
Product Specifications
CAS Number
56605-16-4
Product Name Alternative
NSC172112; NSC268497
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NCI172112.html
Purity
99.08
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(CCCl)CCCl)NC2(CCCCC2)C1=O
Molecular Formula
C14H23Cl2N3O2
Molecular Weight
336.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Brown TD, et al. A phase I trial of spirohydantoin mustard (NSC 172112) in patients with advanced cancer. J Clin Oncol. 1986 Aug;4 (8) :1270-6.|[2]Plowman J, et al. The disposition of spirohydantoin mustard (NSC 172112) in rats and dogs. Xenobiotica. 1979 Jun;9 (6) :379-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
47212151 3x 1.0 µg DNA
TNFRSF21 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details 