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T.cruzi-IN-4

T.cruzi-IN-4 (Compound 21) is an anti-parasitic agent. T.cruzi-IN-4 inhibits the trypomastigote and amastigote form of Trypanosoma cruzi with IC50 of 0.033 μM (120 h), T.cruzi-IN-4 inhibits the promastigote and amastigote form of Leishmania infantum with IC50 of 28.74 and 61.82 μM. T.cruzi-IN-4 inhibits Leishmania amazonensis promastigote form with IC50 of 18.38 μM[1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/t-cruzi-in-4.html

Smiles

O=C(C1=NC2=CC=CC=C2N1)N/N=C/C3=CC=C([N+]([O-])=O)O3

Molecular Formula

C13H9N5O4

Molecular Weight

299.24

References & Citations

[1]Ramos LG, et al., Synthesis and activity of benzimidazole N-Acylhydrazones against Trypanosoma cruzi, Leishmania amazonensis and Leishmania infantum. Bioorg Med Chem Lett. 2024 Jul 2;110:129876.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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