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Pomalidomide-C2-amide-C4-Br

Product Specifications

UNSPSC Description

Pomalidomide-C2-amide-C4-Br is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-C2-amide-C4-Br can be used in the synthesis of PROTACs[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-c2-amide-c4-br.html

Smiles

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCNC(CCCCBr)=O)=CC=C3)=O)=O

Molecular Weight

479.32

References & Citations

[1]Chengchun Zhu, et al. Design, Synthesis and Antitumor Activity of a Novel Class of SHP2 Allosteric Inhibitors with a Furanyl Amide-Based Scaffold. J Med Chem. 2024 Aug 8;67(15):13305-13323.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-164391/Pomalidomide-C2-amide-C4-Br-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-164391/

Clinical Information

No Development Reported

CAS Number

2545963-02-6

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