Pomalidomide-C2-amide-C4-Br
Product Specifications
UNSPSC Description
Pomalidomide-C2-amide-C4-Br is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-C2-amide-C4-Br can be used in the synthesis of PROTACs[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-c2-amide-c4-br.html
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCNC(CCCCBr)=O)=CC=C3)=O)=O
Molecular Weight
479.32
References & Citations
[1]Chengchun Zhu, et al. Design, Synthesis and Antitumor Activity of a Novel Class of SHP2 Allosteric Inhibitors with a Furanyl Amide-Based Scaffold. J Med Chem. 2024 Aug 8;67(15):13305-13323.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164391/Pomalidomide-C2-amide-C4-Br-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164391/
Clinical Information
No Development Reported
CAS Number
2545963-02-6
Curated Selection
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