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FATP1-IN-2

FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM) [1].

Product Specifications

CAS Number

[2650944-83-3]

UNSPSC

12352005

Target

FATP

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fatp1-in-2.html

Purity

98.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CN1CCN(CC1)C2=NC=C(C=C2)F)C3=C(C)N=C4C=CC=CN43

Molecular Formula

C19H20FN5O

Molecular Weight

353.39

References & Citations

[1]Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23 (9) :2560-2565.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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