FATP1-IN-2
FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM) [1].
Product Specifications
CAS Number
[2650944-83-3]
UNSPSC
12352005
Target
FATP
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fatp1-in-2.html
Purity
98.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CN1CCN(CC1)C2=NC=C(C=C2)F)C3=C(C)N=C4C=CC=CN43
Molecular Formula
C19H20FN5O
Molecular Weight
353.39
References & Citations
[1]Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23 (9) :2560-2565.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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