C5A
C5A is a microbicidal peptide, anti-hepatitis C virus (HCV), and anti-HIV agent. C5A disrupts the membrane integrity of the HIV virion as well as the integrity of the conical capsid core that surrounds the viral genome. C5A inhibits in vitro infectivity of a broad range of primary HIV isolates in various primary target cells. C5A protects mice against vaginal and rectal HIV challenges[1].
Product Specifications
CAS Number
811418-15-2
UNSPSC
12352209
Target
HCV; HIV
Type
Peptides
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/c5a.html
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(O)=O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CS)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Molecular Formula
C109H155N25O29S
Molecular Weight
2311.61
References & Citations
[1]Gallay PA, et al. Protection Efficacy of C5A Against Vaginal and Rectal HIV Challenges in Humanized Mice. Open Virol J. 2018 Feb 28;12:1-13.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740253-100 1x 100 µL
Cytokeratin, LMW (AE-1), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680276-100 1x 100 µL
TAG-72 / CA72.4 (B72.3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040637-100 1x 100 µL
Renal Cell Carcinoma (Carbonic Anhydrase IX) (PN-15), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040823-100 1x 100 µL
P21 / WAF1 (CIP1/823), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940226-100 1x 100 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details