(+) -Coclaurine (hydrochloride)

(+) -Coclaurine ((+) - (R) -Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+) -Coclaurine hydrochloride has anti-aging activity[1][2].

Product Specifications

CAS Number

[19894-19-0]

Product Name Alternative

(+) - (R) -Coclaurine (hydrochloride) ; (R) -Coclaurine (hydrochloride) ; d-Coclaurine (hydrochloride)

UNSPSC

12352005

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/plus-coclaurine-hydrochloride.html

Purity

99.09

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)

Smiles

COC(C=C(CCN1)C([C@H]1CC2=CC=C(C=C2)O)=C3)=C3O.Cl

Molecular Formula

C17H20ClNO3

Molecular Weight

321.80

References & Citations

[1][1]Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4 (11) :e00951.|[2]H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6 (10) :793-6.