Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BRPF1B/TRIM24-IN-1

BRPF1B/TRIM24-IN-1 (compound 34) is a potent TRIM24/BRPF1/BRPF2 inhibitor, with IC50 values of 0.43, 0.34, 1.75 μM, respectively. BRPF1B/TRIM24-IN-1 binds the TRIM24 bromodomain with a KD of 222 nM and has a KD for the BRPF1 bromodomain of 137 nM and for BRD1 of 1130 nM[1].

Product Specifications

CAS Number

[1242907-48-7]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brpf1b-trim24-in-1.html

Smiles

O=S(C1=CC=C(OC)C(OC)=C1)(NC2=C(OC3=CC=C(OC)C=C3)C=C(N4C)C(N(C)C4=O)=C2)=O

Molecular Formula

C24H25N3O7S

Molecular Weight

499.54

References & Citations

[1]Bennett J, et al. Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF. J Med Chem. 2016 Feb 25;59 (4) :1642-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

BRPF1; BRPF2

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Anti-ADGRB3 antibody
STJ113872 100 µl

Anti-ADGRB3 antibody

Ask
View Details
SUMO1, NT (SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1) (MaxLight 650)
MBS6352585-01 0.1 mL

SUMO1, NT (SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1) (MaxLight 650)

Ask
View Details
SUMO1, NT (SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1) (MaxLight 650)
MBS6352585-02 5x 0.1 mL

SUMO1, NT (SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1) (MaxLight 650)

Ask
View Details
Furaltadone Metabolite (AMOZ) ELISA BioAssayTM Kit
376900-01 48 Tests

Furaltadone Metabolite (AMOZ) ELISA BioAssayTM Kit

Ask
View Details
Furaltadone Metabolite (AMOZ) ELISA BioAssayTM Kit
376900-02 96 Tests

Furaltadone Metabolite (AMOZ) ELISA BioAssayTM Kit

Ask
View Details
APC_Cy7-Linked Monoclonal Antibody to Cytokeratin 18 (CK18)
MBS2151147-01 0.1 mL

APC_Cy7-Linked Monoclonal Antibody to Cytokeratin 18 (CK18)

Ask
View Details