Endotoxin inhibitor
Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1].
Product Specifications
CAS Number
147396-10-9
UNSPSC
12352209
Target
COX; Interleukin Related
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/endotoxin-inhibitor.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)C(O)=O)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)CCCCN)N[C@H]1CC2=CC=CC=C2
Molecular Formula
C55H97N15O12S2
Molecular Weight
1224.58
References & Citations
[1]Toshihiko Katafuchi, et al. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res Mol Brain Res. 2003 Oct 21;118 (1-2) :24-32.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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