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(Rac) -1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium)

Selected Variant

HY-112307A-01

Size: 50 mg

(Rac) -1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be studied for drug delivery and the synthesis of liposomes. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-containing liposomes can induce Tregs that are specific for the liposomes’ cargo. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is taken up by antigen-presenting cells mediated via complement component 1q (C1q) [1].

Product Specifications

CAS Number

124011-52-5

UNSPSC

12352128

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rac-1-2-distearoyl-sn-glycero-3-phosphatidylglycerol-sodium.html

Purity

99.97

Solubility

10 mM in DMSO

Smiles

O=P(OCC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(OCC(O)CO)O.[x].[Na]

Molecular Formula

C42H83O10P.xNa

Precautions

H302, H315, H319, H335

References & Citations

[1]Naomi Benne, et al. Anionic 1,2-distearoyl-sn-glycero-3-phosphoglycerol (DSPG) liposomes induce antigen-specific regulatory T cells and prevent atherosclerosis in mice. J Control Release. 2018 Dec 10;291:135-146.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

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