Cacaoidin

Product Specifications

UNSPSC Description

Cacaoidin is a glycosylated lantibiotic isolated from a Streptomyces cacaoi strain. Cacaoidin has potent antibacterial activity against Gram-positive pathogens including Clostridium difficile[1].

Target Antigen

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cacaoidin.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](C(N1CCC[C@H]12)=O)NC(C(NC([C@@H](CSC[C@H](NC2=O)C(N[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@@H](C)C(N[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@@H](C(N[C@@H](C)C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC3)=O)CC4=CNC5=C4C=CC=C5)=O)CO)=O)C)=O)[C@H](C)S/C=C\NC3=O)=O)=O)C)=O)=O)C)=O)=O)C)=O)C(C)C)=O)C)=O)=O)CC6=CC=C(C=C6)O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O[C@@H]8[C@H]([C@H]([C@@H]([C@H](C)O8)O)O)O)[C@H]7O)=O)=O)CC)=O)N(C)C)=O)=C)=O

Molecular Weight

2360.70

References & Citations

[1]Ortiz-López FJ, Carretero-Molina D, Sánchez-Hidalgo M, Martín J, González I, Román-Hurtado F, de la Cruz M, García-Fernández S, Reyes F, Deisinger JP, Müller A, Schneider T, Genilloud O. Cacaoidin, First Member of the New Lanthidin RiPP Family. Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12654-12658.