Ubiquitin Activating Enzyme E1 (His-tag) Human Recombinant

<strong>Ubiquitin Activating Enzyme E1 (His-tag) Human Recombinant</strong>_x000D_ <strong>Catalog number:</strong> B2019681_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~119 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Ubiquitin Activating Enzyme E1 (His-tag) human recombinant_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Leidecker O, Matic I, Mahata B, Pion E, Xirodimas DP. The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions Cell Cycle. 2012 Mar 15;11(6):1142-50._x000D_ 2: Ungermannova D, Parker SJ, Nasveschuk CG, Wang W, Quade B, Zhang G, Kuchta RD, Phillips AJ, Liu X. Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1) PLoS One. 2012;7(1):e29208._x000D_ 3: Awasthi S, Dobrolecki LE, Sallas C, Zhang X, Li Y, Khazaei S, Ghosh S, Jeter CR, Liu J, Mills GB, Westin SN, Lewis MT, Peng W, Sood AK, Yap TA, Yi SS, McGrail DJ, Sahni N. UBA1 inhibition sensitizes cancer cells to PARP inhibitors Cell Rep Med. 2024 Dec 17;5(12):101834._x000D_ 4: Ikeda M, Watanabe T, Ito A, Fujimuro M. Herpes simplex virus 1 infection induces ubiquitination of UBE1a Biochem J. 2021 Jan 15;478(1):261-279._x000D_ 5: Yang X, Brownell JE, Xu Q, Zhu F, Ma J, Loke HK, Rollins N, Soucy TA, Minissale JJ, Thomas MP, Mallender WD, Dick LR, Li P, Liao H. Absolute quantification of E1, ubiquitin-like proteins and Nedd8-MLN4924 adduct by mass spectrometry Cell Biochem Biophys. 2013 Sep;67(1):139-47._x000D_ 6: Lv Z, Rickman KA, Yuan L, Williams K, Selvam SP, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, Olsen SK. S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity Mol Cell. 2017 Feb 16;65(4):699-714.e6._x000D_ 7: Narasimhan J, Wang M, Fu Z, Klein JM, Haas AL, Kim JJ. Crystal structure of the interferon-induced ubiquitin-like protein ISG15 J Biol Chem. 2005 Jul 22;280(29):27356-65._x000D_ 8: Lee JG, Youn HS, Kang JY, Park SY, Kidera A, Yoo YJ, Eom SH. Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis Biochem Biophys Res Commun. 2018 Nov 17;506(1):102-107._x000D_ 9: Song AX, Yang H, Gao YG, Zhou CJ, Zhang YH, Hu HY. A ubiquitin shuttle DC-UbP/UBTD2 reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 enzymes PLoS One. 2014 Sep 10;9(9):e107509._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/18583345">10: Durfee LA, Kelley ML, Huibregtse JM. The basis for selective E1-E2 interactions in the ISG15 conjugation system J Biol Chem. 2008 Aug 29;283(35):23895-902. </a>_x000D_ _x000D_ <strong>Products Related to Ubiquitin Activating Enzyme E1 (His-tag) Human Recombinant can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>