6-Chloro-L-tryptophan

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ[1].

Product Specifications

CAS Number

[33468-35-8]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6-chloro-l-tryptophan.html

Purity

99.83

Solubility

DMSO : 2 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic; warming; adjust pH to 12 with 1M NaOH; heat to 60°C)

Smiles

O=C([C@H](CC1=CNC2=C1C=CC(Cl)=C2)N)O

Molecular Formula

C11H11ClN2O2

Molecular Weight

238.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Heemstra JR Jr, et al. Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly. J Am Chem Soc. 2008 Oct 29;130 (43) :14024-5. |[2]Iwasaki M, et al. A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity. Biomed Chromatogr. 2016 Mar;30 (3) :384-9.