Idramantone

Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an Adamantane derivative. Idramantone is an immunostimulant. Idramantone is a versatile starting material for the synthesis of various adamantine deivatives. Idramantone can be produced using P450cam monooxygenase coupled with NADH regeneration as an oxidation biocatalyst. Idramantone can be studied in research on bronchial pathology[1][2][3].

Product Specifications

CAS Number

[20098-14-0]

Product Name Alternative

Kemantane; 5-Hydroxy-2-adamantanone

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Idramantone.html

Concentration

10mM

Purity

99.94

Solubility

H2O : 20 mg/mL (ultrasonic)

Smiles

O=C1C(C2)CC3CC2(O)CC1C3

Molecular Formula

C10H14O2

Molecular Weight

166.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Boĭko SS, et al. Mezhvidovye razlichiia farmakokinetiki kemantana [Interspecific differences in kemantan pharmacokinetics]. Eksp Klin Farmakol. 1994;57 (6) :48-50.|[2]Boĭko SS, et al., The clinical pharmacokinetics of kemantane. Farmakologiia i Toksikologiia, 01 Jan 1991, 54 (1) :57-59.|[3]Toshiki Furuya, et al., Biocatalytic production of 5-hydroxy-2-adamantanone by P450cam coupled with NADH regeneration, Journal of Molecular Catalysis B: Enzymatic, 2013, 94:111-118.