Cyclo(RGDyK)
Product Specifications
UNSPSC Description
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
Target Antigen
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclo-rgdyk.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@@H](N2)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC(O)=O)C2=O)=O)=O)CCCNC(N)=N)=O)CCCCN)=O
Molecular Weight
619.67
References & Citations
[1]Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.Biochem Pharmacol. 2023 Sep 14;115808.|Pharmaceuticals. 2021 Mar 14;14(3):260.|Stem Cell Res Ther. 2022 Jul 18;13(1):327.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100563A/Cyclo-RGDyK-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100563A/Cyclo-RGDyK-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
217099-14-4
Available Sizes
Curated Selection
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