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Cyclo(RGDyK)

Product Specifications

UNSPSC Description

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

Target Antigen

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cyclo-rgdyk.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@@H](N2)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC(O)=O)C2=O)=O)=O)CCCNC(N)=N)=O)CCCCN)=O

Molecular Weight

619.67

References & Citations

[1]Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.Biochem Pharmacol. 2023 Sep 14;115808.|Pharmaceuticals. 2021 Mar 14;14(3):260.|Stem Cell Res Ther. 2022 Jul 18;13(1):327.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100563A/Cyclo-RGDyK-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100563A/Cyclo-RGDyK-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

217099-14-4

Available Sizes

Curated Selection

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