Mal-GGFG-PAB-MMAE
Mal-GGFG-PAB-MMAE (Compound 8) is a drug-linker conjugate, which is composed of the mitotic inhibitor MMAE (HY-15162) and the linker Mal-GGFG-PAB. Mal-GGFG-PAB-MMAE can be used for synthesis of antibody-drug conjugate[1].
Product Specifications
CAS Number
[3055607-18-3]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-ggfg-pab-mmae.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC(CNC([C@@H](NC(CNC(CNC(CCN4C(C=CC4=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)OC)=O
Molecular Formula
C69H97N11O16
Molecular Weight
1336.57
References & Citations
[1]Huang J, et al., Highly stable targeted linker-drug conjugate. US20240293570.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1100607 1.0 µg DNA
IRX5 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
Sign In for Pricing
View Details E28G1899 100 µL
Caspase-7 (Cleaved S199) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
MBS6437411-01 0.1 mL
SH2B1 (SH2B Adapter Protein 1, PSM, SH2B) (FITC)
Sign In for Pricing
View Details MBS6437411-02 5x 0.1 mL
SH2B1 (SH2B Adapter Protein 1, PSM, SH2B) (FITC)
Sign In for Pricing
View Details