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Mal-GGFG-PAB-MMAE

Mal-GGFG-PAB-MMAE (Compound 8) is a drug-linker conjugate, which is composed of the mitotic inhibitor MMAE (HY-15162) and the linker Mal-GGFG-PAB. Mal-GGFG-PAB-MMAE can be used for synthesis of antibody-drug conjugate[1].

Product Specifications

CAS Number

[3055607-18-3]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-ggfg-pab-mmae.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC(CNC([C@@H](NC(CNC(CNC(CCN4C(C=CC4=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)OC)=O

Molecular Formula

C69H97N11O16

Molecular Weight

1336.57

References & Citations

[1]Huang J, et al., Highly stable targeted linker-drug conjugate. US20240293570.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-170512/Mal-GGFG-PAB-MMAE-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-170512/Mal-GGFG-PAB-MMAE-SDS-MedChemExpress.pdf

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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