Hsp90-IN-34
Hsp90-IN-34 (compound HAM-1) is a compound that inhibits the Aha1-Hsp90 chaperone complex with a high affinity for Hsp90/Aha1 (KDapp=23.5 µM) . Hsp90-IN-34 modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1[1].
Product Specifications
CAS Number
439588-33-7
UNSPSC
12352101
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsp90-in-34.html
Smiles
N#CC1=C(N)OC2=C(C1C3=CNN=C3C4=CC=C(F)C=C4)C(C5=CC=C(F)C=C5)=NN2
Molecular Formula
C22H14F2N6O
Molecular Weight
416.38
References & Citations
[1]Stiegler S C, et al. A chemical compound inhibiting the Aha1–Hsp90 chaperone complex[J]. Journal of Biological Chemistry, 2017, 292 (41) : 17073-17083.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC200489L4V 200 µL
CLK3 (NM_003992) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
