Fluorogenic Caspase 1 Substrate 3f

<strong>Fluorogenic Caspase 1 Substrate 3f</strong>_x000D_ <strong>Catalog number:</strong> B2011406_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 838.8 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Caspase 1 (ICE) Substrate 3f, fluorogenic_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Boucher D, Chan A, Ross C, Schroder K. Quantifying Caspase-1 Activity in Murine Macrophages Methods Mol Biol. 2018;1725:163-176._x000D_ 2: Qian L, Zhang CJ, Wu J, Yao SQ. Fused Bicyclic Caspase-1 Inhibitors Assembled by Copper-Free Strain-Promoted Alkyne-Azide Cycloaddition (SPAAC) Chemistry. 2017 Jan 5;23(2):360-369._x000D_ 3: Rahman MA, Mitra S, Sarkar A, Wewers MD. Alpha 1-antitrypsin does not inhibit human monocyte caspase-1 PLoS One. 2015 Feb 6;10(2):e0117330._x000D_ 4: Schumann RR, Belka C, Reuter D, Lamping N, Kirschning CJ, Weber JR, Pfeil D. Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells Blood. 1998 Jan 15;91(2):577-84._x000D_ 5: Kindermann M, Roschitzki-Voser H, Caglic D, Repnik U, Miniejew C, Mittl PR, Kosec G, Grütter MG, Turk B, Wendt KU. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe Chem Biol. 2010 Sep 24;17(9):999-1007._x000D_ 6: Ranganathan R, Lenti G, Tassone NM, Scannell BJ, Southern CA, Karver CE. Design and application of a fluorogenic assay for monitoring inflammatory caspase activity Anal Biochem. 2018 Feb 15;543:1-7._x000D_ 7: Fahy RJ, Doseff AI, Wewers MD. Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1 J Immunol. 1999 Aug 15;163(4):1755-62._x000D_ 8: Karahashi H, Amano F. Changes of caspase activities involved in apoptosis of a macrophage-like cell line J774.1/JA-4 treated with lipopolysaccharide (LPS) and cycloheximide Biol Pharm Bull. 2000 Feb;23(2):140-4._x000D_ 9: Li M, Ona VO, Chen M, Kaul M, Tenneti L, Zhang X, Stieg PE, Lipton SA, Friedlander RM. Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury Neuroscience. 2000;99(2):333-42._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/18332441">10: Roy S, Sharom JR, Houde C, Loisel TP, Vaillancourt JP, Shao W, Saleh M, Nicholson DW. Confinement of caspase-12 proteolytic activity to autoprocessing Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4133-8. </a>_x000D_ _x000D_ <strong>Products Related to Fluorogenic Caspase 1 Substrate 3f can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>