Endostatin (Human, Recombinant)

<strong>Endostatin (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010299_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Endostatin (Human, Recombinant) expressed in P. pastoris. This protein acts as an endogenous antiangiogenic peptide with multiple antitumor roles that stem from the modulation of various receptors in the plasma membrane._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuEndostatin; Collagen alpha-1(XV) chain_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Walia A, Yang JF, Huang YH, Rosenblatt MI, Chang JH, Azar DT. Endostatin's_x000D_ emerging roles in angiogenesis, lymphangiogenesis, disease, and clinical_x000D_ applications. Biochim Biophys Acta. 2015 Dec;1850(12):2422-38._x000D_ PMC4624607._x000D_ _x000D_ 2: Fu Y, Tang H, Huang Y, Song N, Luo Y. Unraveling the mysteries of endostatin._x000D_ IUBMB Life. 2009 Jun;61(6):613-26._x000D_ _x000D_ 3: Lamattina AM, Poli S, Kidambi P, Bagwe S, Courtwright A, Louis PH, Shrestha_x000D_ S, Stump B, Goldberg HJ, Thiele EA, Rosas I, Henske EP, El-Chemaly S. Serum_x000D_ endostatin levels are associated with diffusion capacity and with tuberous_x000D_ sclerosis- associated lymphangioleiomyomatosis. Orphanet J Rare Dis. 2019 Mar_x000D_ 29;14(1):72._x000D_ _x000D_ 4: Shah I, Malik MO, Khan MJ, Fatima S, Baxendale RH, Habib SH. Endostatin_x000D_ Concentration In Plasma Of Healthy Human Volunteers. J Ayub Med Coll Abbottabad._x000D_ 2017 Apr-Jun;29(2):200-206._x000D_ _x000D_ 5: Carlsson AC, Wessman T, Larsson A, Leijonberg G, Tofik R, Ärnlöv J, Melander_x000D_ O, Ruge T. Endostatin predicts mortality in patients with acute dyspnea - A_x000D_ cohort study of patients seeking care in emergency departments. Clin Biochem._x000D_ 2020 Jan;75:35-39._x000D_ _x000D_ 6: Zheng MJ. Endostatin derivative angiogenesis inhibitors. Chin Med J (Engl)._x000D_ 2009 Aug 20;122(16):1947-51._x000D_ _x000D_ 7: Sato Y. Endostatin as a Biomarker of Basement Membrane Degradation. J_x000D_ Atheroscler Thromb. 2017 Oct 1;24(10):1014-1015._x000D_ _x000D_ 8: Karamouzis MV, Moschos SJ. The use of endo_statin in the treatment of solid_x000D_ tumors. Expert Opin Biol Ther. 2009 May;9(5):641-8._x000D_ _x000D_ 9: Barroso MC, Boehme P, Kramer F, Mondritzki T, Koehler T, Gülker JE, Karoff M,_x000D_ Dinh W. Endo_statin a Potential Biomarker for Heart Failure with Preserved_x000D_ Ejection Fraction. Arq Bras Cardiol. 2017 Nov;109(5):448-456._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24390105/">10: Yamaguchi Y, Feghali-Bostwick CA. Role of endostatin in fibroproliferative_x000D_ disorders.-as a candidate for anti-fibrosis therapy-. Nihon Rinsho Meneki Gakkai_x000D_ Kaishi. 2013;36(6):452-8.</a>_x000D_ _x000D_ <strong>Products Related to Endostatin (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>