WS009B
WS009B is a selective endothelin receptor antagonist (ET-1: IC50=0.67 μM; ET-2: IC50=0.8 μM) . WS009B can be used in the study of cardiovascular diseases[1].
Product Specifications
CAS Number
136286-50-5
UNSPSC
12352005
Target
Endothelin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ws009b.html
Smiles
O=C(O)[C@H](CSC1(C(C2=C3C=CC=C2O)=O)C(O)CC(CC(C)=CC4=O)(O)C4(O)C1(O)C3=O)NC(C)=O
Molecular Formula
C24H25NO11S
Molecular Weight
535.52
References & Citations
[1]MIYATA S, et al. WS009 A and B, new endothelin receptor antagonists isolated from Streptomyces sp. No. 89009 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities[J]. The Journal of Antibiotics, 1992, 45 (7) : 1029-1040.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ETA; ETB
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