Ent-Avibactam (sodium)
Ent-Avibactam sodium (AVE1330A) is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), ent-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of ent-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes[1].
Product Specifications
CAS Number
[396731-20-7]
Product Name Alternative
AVE1330A
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ent-avibactam-sodium.html
Smiles
NC([C@@H]1[N@]2C(N([C@@H](CC1)C2)OS(=O)(O[Na])=O)=O)=O
Molecular Formula
C7H10N3NaO6S
Molecular Weight
287.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal TTF-1 / NKX2-1 Antibody (8G7G3/1 + NX2.1/690) [Alexa Fluor 532]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
Mouse Monoclonal TTF-1 / NKX2-1 Antibody (8G7G3/1 + NX2.1/690) [Alexa Fluor 532]
