Casticin (Standard)

Casticin (Standard) is the analytical standard of Casticin. This product is intended for research and analytical applications. Casticin is a methyoxylated flavonol isolated from Vitex rotundifolia, with antimitotic and anti-inflammatory effect. Casticin inhibits the activation of STAT3.

Product Specifications

CAS Number

[479-91-4]

Product Name Alternative

Vitexicarpin (Standard)

UNSPSC

12352005

Target

Reference Standards; STAT

Type

Reference Standards

Related Pathways

JAK/STAT Signaling; Others; Stem Cell/Wnt

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/casticin-standard.html

Smiles

O=C1C(OC)=C(C2=CC=C(OC)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13

Molecular Formula

C19H18O8

Molecular Weight

374.34

References & Citations

[1]Kobayakawa J, et al. G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.) . Cancer Lett. 2004 May 10;208 (1) :59-64.|[2]Zhou L, et al. Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway. Oncotarget. 2017 Apr 27;8 (34) :56267-56280.|[3]Lee JH, et al. Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade. J Cell Biochem. 2018 Dec 5.