Casticin (Standard)
Casticin (Standard) is the analytical standard of Casticin. This product is intended for research and analytical applications. Casticin is a methyoxylated flavonol isolated from Vitex rotundifolia, with antimitotic and anti-inflammatory effect. Casticin inhibits the activation of STAT3.
Product Specifications
CAS Number
479-91-4
Product Name Alternative
Vitexicarpin (Standard)
UNSPSC
12352005
Target
Reference Standards; STAT
Type
Reference Standards
Related Pathways
JAK/STAT Signaling; Others; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/casticin-standard.html
Smiles
O=C1C(OC)=C(C2=CC=C(OC)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13
Molecular Formula
C19H18O8
Molecular Weight
374.34
References & Citations
[1]Kobayakawa J, et al. G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.) . Cancer Lett. 2004 May 10;208 (1) :59-64.|[2]Zhou L, et al. Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway. Oncotarget. 2017 Apr 27;8 (34) :56267-56280.|[3]Lee JH, et al. Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade. J Cell Biochem. 2018 Dec 5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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