NG-497
NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].
Product Specifications
CAS Number
[2598242-66-9]
UNSPSC
12352005
Target
ATGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ng-497.html
Concentration
10mM
Purity
99.07
Solubility
DMSO : 70 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(OC)=CC(C2=CC=C(OCC)C=C2)=N1)OC(C)C
Molecular Formula
C18H21NO4
Molecular Weight
315.36
References & Citations
[1]Gernot F Grabner, et al. Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes. J Am Chem Soc. 2022 Apr 13;144 (14) :6237-6250.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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