NG-497

NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].

Product Specifications

CAS Number

[2598242-66-9]

UNSPSC

12352005

Target

ATGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ng-497.html

Concentration

10mM

Purity

99.07

Solubility

DMSO : 70 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(OC)=CC(C2=CC=C(OCC)C=C2)=N1)OC(C)C

Molecular Formula

C18H21NO4

Molecular Weight

315.36

References & Citations

[1]Gernot F Grabner, et al. Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes. J Am Chem Soc. 2022 Apr 13;144 (14) :6237-6250.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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