NCGC00135472
NCGC00135472 is a potent agonist of resolvin D1 receptor (DRV1), with the EC50 of 0.37 nM and 0.05 μM for β-arrestin and cAMP activities, respectively[1].
Product Specifications
CAS Number
862811-76-5
UNSPSC
12352005
Target
Arrestin
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ncgc00135472.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(C2=C(C)N3C=CC=NC3=N2)=C1)C4=CC=C(F)C(F)=C4
Molecular Formula
C20H14F2N4O
Molecular Weight
364.35
References & Citations
[1]Nan Chiang, et al. Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions. Cell Chem Biol. 2019 Feb 21;26 (2) :244-254.e4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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