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Bazedoxifene (acetate) -B

Bazedoxifene (acetate) -B (TSE-424 (acetate) -B) is the B-crystal form compound of Bazedoxifene acetate. Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively[1].

Product Specifications

CAS Number

198481-33-3

Product Name Alternative

TSE-424 (acetate) -B

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bazedoxifene-acetate-b.html

Purity

99.40

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC1=C(C2=CC=C(O)C=C2)N(CC3=CC=C(OCCN4CCCCCC4)C=C3)C5=CC=C(O)C=C51.CC(O)=O

Molecular Formula

C32H38N2O5

Molecular Weight

530.65

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Barry S Komm, et al. Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology. 2005 Sep;146 (9) :3999-4008.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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