1- (2,3-Dichlorphenyl) piperazine

1- (2,3-Dichlorphenyl) piperazine is a potent DHCR7 inhibitor with the activity of inhibiting cholesterol biosynthesis. 1- (2,3-Dichlorphenyl) piperazine is often used in biological research to evaluate the function of cholesterol biosynthesis pathway. The application of 1- (2,3-Dichlorphenyl) piperazine is of great significance for understanding diseases related to cholesterol biosynthesis[1].

Product Specifications

CAS Number

[41202-77-1]

UNSPSC

12352005

Hazard Statement

H302

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-2-3-dichlorphenyl-piperazine.html

Purity

99.25

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=C(Cl)C(N2CCNCC2)=CC=C1

Molecular Formula

C10H12Cl2N2

Molecular Weight

231.12

Precautions

H302

References & Citations

[1]Rmandić M, et al. Quantification of Zonisamide in Dried Blood Spots and Dried Plasma Spots by UPLC-MS/MS: Application to Clinical Practice. Molecules. 2022 Jul 31;27 (15) :4899.