Evocalcet (Standard)
Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism[1][2].
Product Specifications
CAS Number
870964-67-3
Product Name Alternative
KHK7580 (Standard)
UNSPSC
12352005
Target
CaSR; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/evocalcet-standard.html
Smiles
O=C(O)CC1=CC=C(N2C[C@@H](N[C@@H](C3=C4C=CC=CC4=CC=C3)C)CC2)C=C1
Molecular Formula
C24H26N2O2
Molecular Weight
374.48
References & Citations
[1]Sakai M, et al. Evocalcet prevents ectopic calcification and parathyroid hyperplasia in rats with secondary hyperparathyroidism. PLoS One. 2020 Apr 28;15 (4) :e0232428.|[2]Kawata T, et al. A novel calcimimetic agent, evocalcet (MT-4580/KHK7580), suppresses the parathyroid cell function with little effect on the gastrointestinal tract or CYP isozymes in vivo and in vitro. PLoS One. 2018 Apr 3;13 (4) :e0195316.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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