Tyrosinase-IN-11
Tyrosinase-IN-11 is a potent tyrosinase inhibitor with IC50s of 50 nM and 64 nM for L-tyrosinase and L-dopa, respectively. Tyrosinase-IN-11 has significant antioxidant activity and low cytotoxicity. Tyrosinase-IN-11 has the potential for skin hyperpigmentation research[1].
Product Specifications
CAS Number
240797-64-2
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-11.html
Purity
98.12
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C=C(C=C1)O)O)CCC2=CC=C(C=C2O)O
Molecular Formula
C15H14O5
Molecular Weight
274.27
Precautions
H315, H319, H335
References & Citations
[1]Songtao Xue, et al. Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation. J Med Chem. 2023 Apr 13;66 (7) :5099-5117.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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