Tyrosinase-IN-11

Tyrosinase-IN-11 is a potent tyrosinase inhibitor with IC50s of 50 nM and 64 nM for L-tyrosinase and L-dopa, respectively. Tyrosinase-IN-11 has significant antioxidant activity and low cytotoxicity. Tyrosinase-IN-11 has the potential for skin hyperpigmentation research[1].

Product Specifications

CAS Number

[240797-64-2]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tyrosinase-in-11.html

Purity

98.12

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C=C(C=C1)O)O)CCC2=CC=C(C=C2O)O

Molecular Formula

C15H14O5

Molecular Weight

274.27

Precautions

H315, H319, H335

References & Citations

[1]Songtao Xue, et al. Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation. J Med Chem. 2023 Apr 13;66 (7) :5099-5117.