ORG 33628
ORG 33628 is a potent and selective progesterone receptor modulator. ORG 33628 shows anti-progestational and anti-glucocorticoid activity. ORG 33628 shows ovulation-inhibitory activity. ORG 33628 has the potential for the research of breast and endometrium[1][2].
Product Specifications
CAS Number
155768-17-5
UNSPSC
12352005
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/org-33628.html
Smiles
C[C@@]12[C@]3(C(CCO3)=C)CC[C@@]1([H])[C@@]4([H])C([C@@H](C5=CC=C(C=C5)C(C)=O)C2)=C6C(CC4)=CC(CC6)=O
Molecular Formula
C30H34O3
Molecular Weight
442.59
References & Citations
[1]Kloosterboer HJ, et al. Preclinical experience with two selective progesterone receptor modulators on breast and endometrium. Steroids. 2000 Oct-Nov;65 (10-11) :733-40.|[2]Kloosterboer HJ, et al. Pharmacological properties of a new selective antiprogestagen: Org 33628. Ann N Y Acad Sci. 1995 Jun 12;761:192-201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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