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ORG 33628

ORG 33628 is a potent and selective progesterone receptor modulator. ORG 33628 shows anti-progestational and anti-glucocorticoid activity. ORG 33628 shows ovulation-inhibitory activity. ORG 33628 has the potential for the research of breast and endometrium[1][2].

Product Specifications

CAS Number

155768-17-5

UNSPSC

12352005

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/org-33628.html

Smiles

C[C@@]12[C@]3(C(CCO3)=C)CC[C@@]1([H])[C@@]4([H])C([C@@H](C5=CC=C(C=C5)C(C)=O)C2)=C6C(CC4)=CC(CC6)=O

Molecular Formula

C30H34O3

Molecular Weight

442.59

References & Citations

[1]Kloosterboer HJ, et al. Preclinical experience with two selective progesterone receptor modulators on breast and endometrium. Steroids. 2000 Oct-Nov;65 (10-11) :733-40.|[2]Kloosterboer HJ, et al. Pharmacological properties of a new selective antiprogestagen: Org 33628. Ann N Y Acad Sci. 1995 Jun 12;761:192-201.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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