DL002

DL002 is a ADC linker that can be used to synthesize antibody-drug conjugates containing BCL-2 family protein degraders, and it's used in tumor research[1].

Product Specifications

CAS Number

[3049680-91-0]

UNSPSC

12352203

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dl002.html

Smiles

CC(C)(C1)CCC(C2=CC=C(C=C2)Cl)=C1CN3CCN(C4=CC=C(C=C4)C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(C=C5)N[C@@H](CSC6=CC=CC=C6)CCN7CCN(CC7)C(CCCCCC(N[C@@H](C(C)(C)C)C(N8[C@@H](C[C@H](C8)OC(OCC9=CC=C(C=C9)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CCCCCN%10C=C(C%11=CN=C(S(C)(=O)=O)N=C%11)N=N%10)=O)=O)=O)=O)C(N[C@H](C%12=CC=C(C%13=C(C)N=CS%13)C=C%12)C)=O)=O)=O)=O)=O)=O)CC3

Molecular Formula

C109H139ClF3N19O17S5

Molecular Weight

2240.16

References & Citations

[1]Cai, jiaqiang, et al. Antibody-drug conjugate containing BCL-2 family protein degrader and preparation method and use thereof. CN2024/073029. 2024-07-25.