TIM-098a
TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. TIM-098a has no inhibitory activity against CaMKK isoforms. TIM-098a inhibits AAK1-regulated endocytosis by suppressing AAK1 kinase activity[1].
Product Specifications
UNSPSC
12352005
Target
AAK1
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tim-098a.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC2=CC(O)=CC3=C12)N4C3=NC5=CC(N)=CC=C54
Molecular Formula
C18H11N3O2
Molecular Weight
301.30
References & Citations
[1]Akari Yoshida, et al. Development of a novel AAK1 inhibitor via Kinobeads-based screening. Sci Rep. 2024 Mar 20;14 (1) :6723.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MUC5AC
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MPC0398K Each
Magic™ Membrane Protein Human AQP9 (Aquaporin 9) Full Length
Sign In for Pricing
View Details K6352002 1.0 µg DNA
Rbm20 sgRNA CRISPR Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details NBP2-12185JF549 0.1 mL
Mouse Monoclonal CD94 Antibody (MM0181-5F26) [Janelia Fluor 549]
Sign In for Pricing
View Details 
MBS4380493-01 0.02 mg (With BSA & Azide at 0.2mg/mL)
Spectrin beta III (SPTBN2)
Sign In for Pricing
View Details