Neutrophil elastase inhibitor 1
Neutrophil elastase inhibitor 1 (Compound 5b) is a competitive, pseudoirreversible inhibitor for neutrophil elastase with an IC50 of 7 nM[1].
Product Specifications
CAS Number
1448314-31-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Elastase; Ser/Thr Protease; Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/neutrophil-elastase-inhibitor-1.html
Smiles
N#CC1=NN(C2=C1C=CC=C2)C(C3=CC=CC(C)=C3)=O
Molecular Formula
C16H11N3O
Molecular Weight
261.28
Precautions
P261-P280-P302+P352
References & Citations
[1]Crocetti L, et al., Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. J Med Chem. 2013 Aug 8;56 (15) :6259-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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