Mc-Phe-Lys-PAB-MMAE
Mc-Phe-Lys-PAB-MMAE (Compound 2) is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs[1].
Product Specifications
CAS Number
[646502-54-7]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-phe-lys-pab-mmae.html
Purity
96.82
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CN([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)CCC1)=O)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCCN)NC([C@H](CC4=CC=CC=C4)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O
Molecular Formula
C72H106N10O14
Molecular Weight
1335.67
References & Citations
[1]Doronina SO, et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat Biotechnol. 2003 Jul;21 (7) :778-84.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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