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Levomenol

Levomenol ((-) -α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active[1][2].

Product Specifications

CAS Number

[23089-26-1]

Product Name Alternative

(-) -α-Bisabolol

UNSPSC

12352211

Hazard Statement

H315, H319, H320

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/levomenol.html

Concentration

10mM

Purity

99.22

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@](O)([C@@]1([H])CCC(C)=CC1)CC/C=C(C)/C

Molecular Formula

C15H26O

Molecular Weight

222.37

Precautions

H315, H319, H320

References & Citations

[1]Fernandes MYD, et al. (-) -α-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Eur J Pharmacol. 2019 Jan 5;842:270-280.|[2]Melo LT, et al. (-) -α-Bisabolol reduces nociception and trigeminal central sensitisation in acute orofacial neuropathic pain induced by infraorbital nerve injury. Life Sci. 2019 Jun 15;227:122-128.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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