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Dihydroartemisinin

Product Specifications

UNSPSC Description

Dihydroartemisinin is a potent anti-malaria agent.

Target Antigen

Apoptosis; Autophagy; NF-κB; Parasite

Type

Natural Products

Related Pathways

Anti-infection;Apoptosis;Autophagy;NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/Dihydroartemisinin.html

Purity

99.03

Solubility

DMSO : 25 mg/mL (ultrasonic)|Ethanol : 10 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1

Molecular Weight

284.352

References & Citations

[1]Hu W, et al. Dihydroartemisinin induces autophagy by suppressing NF-κB activation. Cancer Lett. 2014 Feb 28;343(2):239-48.|[2]Li YJ, et al. Dihydroartemisinin accentuates the anti-tumor effects of photodynamic therapy via inactivation of NF-κB in Eca109 and Ec9706 esophageal cancer cells. Cell Physiol Biochem. 2014;33(5):1527-36.|[3]Li HJ, et al. Dihydroartemisinin-praziquantel combinations and multiple doses of dihydroartemisinin in the treatment of Schistosoma japonicum in experimentally infected mice. Ann Trop Med Parasitol. 2011 Jun;105(4):329-33.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0176/Dihydroartemisinin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0176/Dihydroartemisinin-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

71939-50-9

Available Sizes

Curated Selection

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