Dihydroartemisinin

Dihydroartemisinin is a potent anti-malaria agent.

Product Specifications

CAS Number

[71939-50-9]

Product Name Alternative

Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol

UNSPSC

12352005

Hazard Statement

H242, H411

Target

Apoptosis; Autophagy; NF-κB; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/Dihydroartemisinin.html

Purity

99.03

Solubility

DMSO : 25 mg/mL (ultrasonic) |Ethanol : 10 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1

Molecular Formula

C15H24O5

Molecular Weight

284.35

Precautions

H242, H411

References & Citations

[1]Hu W, et al. Dihydroartemisinin induces autophagy by suppressing NF-κB activation. Cancer Lett. 2014 Feb 28;343 (2) :239-48.|[2]Li YJ, et al. Dihydroartemisinin accentuates the anti-tumor effects of photodynamic therapy via inactivation of NF-κB in Eca109 and Ec9706 esophageal cancer cells. Cell Physiol Biochem. 2014;33 (5) :1527-36.|[3]Li HJ, et al. Dihydroartemisinin-praziquantel combinations and multiple doses of dihydroartemisinin in the treatment of Schistosoma japonicum in experimentally infected mice. Ann Trop Med Parasitol. 2011 Jun;105 (4) :329-33.