Dihydroartemisinin
Dihydroartemisinin is a potent anti-malaria agent.
Product Specifications
CAS Number
71939-50-9
Product Name Alternative
Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol
UNSPSC
12352005
Hazard Statement
H242, H411
Target
Apoptosis; Autophagy; NF-κB; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Dihydroartemisinin.html
Purity
99.03
Solubility
DMSO : 25 mg/mL (ultrasonic) |Ethanol : 10 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1
Molecular Formula
C15H24O5
Molecular Weight
284.35
Precautions
H242, H411
References & Citations
[1]Hu W, et al. Dihydroartemisinin induces autophagy by suppressing NF-κB activation. Cancer Lett. 2014 Feb 28;343 (2) :239-48.|[2]Li YJ, et al. Dihydroartemisinin accentuates the anti-tumor effects of photodynamic therapy via inactivation of NF-κB in Eca109 and Ec9706 esophageal cancer cells. Cell Physiol Biochem. 2014;33 (5) :1527-36.|[3]Li HJ, et al. Dihydroartemisinin-praziquantel combinations and multiple doses of dihydroartemisinin in the treatment of Schistosoma japonicum in experimentally infected mice. Ann Trop Med Parasitol. 2011 Jun;105 (4) :329-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Plasmodium; RelA/p65
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