TRAF6 peptide
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].
Product Specifications
CAS Number
852805-92-6
UNSPSC
12352209
Target
E1/E2/E3 Enzyme; p62
Type
Peptides
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/traf6-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C(CNC([C@H](CO)NC([C@H](C)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]2N(CCC2)C([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCCN)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C145H238N34O44
Molecular Weight
3161.64
References & Citations
[1]Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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