HBV-IN-47

HBV-IN-47 (compound 4a) is a capsid assembly regulator with inhibitory activity against hepatitis B virus (HBV) . HBV-IN-47 exhibits strong anti-HBV activity in HepAD38 cells with low toxicity (EC50=0.24 μM) . HBV-IN-47 can be used for the study of chronic hepatitis B (CHB) [1].

Product Specifications

UNSPSC

12352211

Target

HBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hbv-in-47.html

Smiles

O=C(NC1=CC(F)=C(F)C(F)=C1)C2=CC(S(=O)(NC3CCCC3)=O)=CC4=C2OCCO4

Molecular Formula

C20H19F3N2O5S

Molecular Weight

456.44

References & Citations

[1]M Liang, et al. "Design, synthesis and anti-HBV activity study of novel HBV capsid assembly modulators." Bioorganic & Medicinal Chemistry Letters (2024) : 129913.