Human Activin B

<strong>Human Activin B</strong>_x000D_ <strong>Catalog number:</strong> B2018708_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~13 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Activin B, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jin Y, Cai Q, Wang L, Ji J, Sun Y, Jiang J, Wang C, Wu J, Zhang B, Zhao L, Qi F, Yu B, Zhang J. Paracrine activin B-NF-κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming J Exp Clin Cancer Res. 2023 Oct 19;42(1):269._x000D_ 2: Ganz T. Systemic iron homeostasis Physiol Rev. 2013 Oct;93(4):1721-41._x000D_ 3: Meng Q, Xia Y. c-Jun, at the crossroad of the signaling network Protein Cell. 2011 Nov;2(11):889-98._x000D_ 4: Li Y, Klausen C, Cheng JC, Zhu H, Leung PC. Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin J Clin Endocrinol Metab. 2014 Nov;99(11):E2216-25._x000D_ 5: Xiong S, Klausen C, Cheng JC, Zhu H, Leung PC. Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling Oncotarget. 2015 Oct 13;6(31):31659-73._x000D_ 6: Wang Y, Hamang M, Culver A, Jiang H, Yanum J, Garcia V, Lee J, White E, Kusumanchi P, Chalasani N, Liangpunsakul S, Yaden BC, Dai G. Activin B promotes the initiation and progression of liver fibrosis Hepatol Commun. 2022 Oct;6(10):2812-2826._x000D_ 7: Richani D, Constance K, Lien S, Agapiou D, Stocker WA, Hedger MP, Ledger WL, Thompson JG, Robertson DM, Mottershead DG, Walton KL, Harrison CA, Gilchrist RB. Cumulin and FSH Cooperate to Regulate Inhibin B and Activin B Production by Human Granulosa-Lutein Cells In Vitro Endocrinology. 2019 Apr 1;160(4):853-862._x000D_ 8: Krepinsky JC. Activin B, a new player in kidney fibrosis?(†) J Pathol. 2022 Apr;256(4):363-365._x000D_ 9: Billings PC, Bizzaro C, Yang E, Chung J, Mundy C, Pacifici M. Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin_B PLoS One. 2020 Feb 19;15(2):e0229254._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26001835">10: Chang HM, Cheng JC, Huang HF, Shi FT, Leung PC. Activin A, B and AB decrease progesterone production by down-regulating StAR in human granulosa cells Mol Cell Endocrinol. 2015 Sep 5;412:290-301. </a>_x000D_ _x000D_ <strong>Products Related to Human Activin B can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>