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Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (Y45)

Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (Y45) is a neutralizing mouse monoclonal antibody produced from hybridoma.

Product Specifications

Background

FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

CAS Number

9007-83-4

Host

Hybridoma

Origin Species

Mouse

Target

FMC63

Conjugation

Unconjugated

Applications

Flow Cytometry (Evaluation of Anti-CD19 (FMC63 scFv) CAR Expression) .

Stability

-20°C to -70°C for 24 months in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Format

Powder

Buffer

PBS, 0.5% BSA, pH7.4

Additives

Trehalose

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

250tests*1

Host or Source

Hybridoma

Species

Mouse

Preservative

Trehalose

Curated Selection

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