Ramatercept

Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy[1][2][3].

Product Specifications

CAS Number

[1169766-01-1]

Product Name Alternative

ACE-031

UNSPSC

12352203

Target

TGF-β Receptor

Type

Inhibitory Antibodies

Related Pathways

TGF-beta/Smad

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ramatercept.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

[Ramatercept]

Molecular Weight

(77.24 kDa)

References & Citations

[1]Fariello R G, et al. A novel Biological (FOX-115) improves endurance of motor performances in old mice (P2. 4-033) [J]. 2019.|[2]Feike Y, et al. Advances in research on pharmacotherapy of sarcopenia. Aging Med (Milton) . 2021 Aug 9;4 (3) :221-233. |[3]Louvel É. Dopage: nouveaux médicaments influant sur la biogenèse musculaire et mitochondriale[J]. 2019.