Ramatercept
Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy[1][2][3].
Product Specifications
CAS Number
[1169766-01-1]
Product Name Alternative
ACE-031
UNSPSC
12352203
Target
TGF-β Receptor
Type
Inhibitory Antibodies
Related Pathways
TGF-beta/Smad
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ramatercept.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
[Ramatercept]
Molecular Weight
(77.24 kDa)
References & Citations
[1]Fariello R G, et al. A novel Biological (FOX-115) improves endurance of motor performances in old mice (P2. 4-033) [J]. 2019.|[2]Feike Y, et al. Advances in research on pharmacotherapy of sarcopenia. Aging Med (Milton) . 2021 Aug 9;4 (3) :221-233. |[3]Louvel É. Dopage: nouveaux médicaments influant sur la biogenèse musculaire et mitochondriale[J]. 2019.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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