Anticancer agent 222

Anticancer agent 222 (Compound 19) is an orally active anticancer agent that exhibits significant anticancer activity against Huh7, FOCUS, SNU475, SNU182, HepG2, and Hep3B cells (IC50 = 2.9–9.3 μM) [1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-222.html

Smiles

FC(F)(F)C(C=C1)=CC=C1C2=NC3=C(N=CN=C3N2C4CCCC4)N(CC5)CCN5C6=CC=C(C(F)(F)F)C=C6

Molecular Formula

C28H26F6N6

Molecular Weight

560.54

References & Citations

[1]Fatih Polat M, et al. Synthesis and cytotoxicity of novel 6,8,9-trisubstituted purine analogs against liver cancer cells. Bioorg Med Chem Lett. 2024;106:129775.