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Fenoldopam (mesylate) (Standard)

Fenoldopam (mesylate) (Standard) is the analytical standard of Fenoldopam (mesylate) . This product is intended for research and analytical applications. Fenoldopam mesylate (SKF-82526) is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM) . Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis[1][2][3].

Product Specifications

CAS Number

67227-57-0

Product Name Alternative

Fenoldopam (methanesulfonate) (Standard) ; SKF-82526 (mesylate) (Standard)

UNSPSC

12352005

Target

Apoptosis; Dopamine Receptor; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fenoldopam-mesylate-standard.html

Smiles

OC1=C(O)C=C2C(C3=CC=C(O)C=C3)CNCCC2=C1Cl.CS(=O)(O)=O

Molecular Formula

C17H20ClNO6S

Molecular Weight

401.86

References & Citations

[1]A Grenader, et al. Fenoldopam is a partial agonist at dopamine-1 (DA1) receptors in LLC-PK1 cells. J Pharmacol Exp Ther. 1991 Jul 1;258 (1) :193-8.|[2]Yan Zheng, et al. Identification of fenoldopam as a novel LSD1 inhibitor to abrogate the proliferation of renal cell carcinoma using drug repurposing strategy. Bioorg Chem. 2021 Mar;108:104561.|[3]Yuta Fujii, et al. Detection of fenoldopam-induced arteritis in rats using ex vivo / in vivo MRI. Toxicology Reports, Volume 9, 2022, Pages 1595-1602.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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